Anti-CRYZ antibody (275-325 aa) (STJ195597)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human QOR at the amino acid range 275-325
General Information
| Short Description | Rabbit polyclonal anti-Quinone oxidoreductase (275-325 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRYZ |
| Gene ID | 1429 |
| Uniprot ID | QOR_HUMAN |
| Immunogen | Synthesized peptide derived from the human QOR at the amino acid range 275-325 |
| Immunogen Region | 275-325 aa |
| Specificity | This antibody detects endogenous levels of QOR at Human/Mouse/Rat |
Additional Info
| Function | Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding. |
| Protein Name | Quinone OxidoreductaseNadph -Quinone ReductaseZeta-Crystallin |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Quinone Oxidoreductase antibodyAnti-Nadph -Quinone Reductase antibodyAnti-Zeta-Crystallin antibodyAnti-CRYZ antibody |
Information sourced from Uniprot.org