| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CRYM (1-314) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CRYM |
| Gene ID: |
1428 |
| Uniprot ID: |
CRYM_HUMAN |
| Immunogen Region: |
1-314 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-314 of human CRYM (NP_001879.1). |
| Immunogen Sequence: |
MSRVPAFLSAAEVEEHLRSS SLLIPPLETALANFSSGPEG GVMQPVRTVVPVTKHRGYLG VMPAYSAAEDALTTKLVTFY EDRGITSVVPSHQATVLLFE PSNGTLLAVMDGNVITAKRT AAVSAIATKFLKPPSSEVLC ILGAGVQAYSHYEIFTEQFS FKEVRIWNRTKENAEKFADT VQGEVRVCSSVQEAVAGADV IITVTLATEPILFGEWVKPG AHINAVGASRPDWRELDDE |
| Tissue Specificity | Expressed in neural tissue, muscle and kidney. |
| Function | Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors. |
| Protein Name | Ketimine Reductase Mu-CrystallinNadp-Regulated Thyroid-Hormone-Binding Protein |
| Database Links | Reactome: R-HSA-71064 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ketimine Reductase Mu-Crystallin antibodyAnti-Nadp-Regulated Thyroid-Hormone-Binding Protein antibodyAnti-CRYM antibodyAnti-THBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
