Anti-CRYBB1 antibody (1-252) (STJ11100891)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CRYBB1 (1-252) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRYBB1 |
| Gene ID | 1414 |
| Uniprot ID | CRBB1_HUMAN |
| Immunogen Region | 1-252 |
| Immunogen Sequence | MSQAAKASASATVAVNPGPD TKGKGAPPAGTSPSPGTTLA PTTVPITSAKAAELPPGNYR LVVFELENFQGRRAEFSGEC SNLADRGFDRVRSIIVSAGP WVAFEQSNFRGEMFILEKGE YPRWNTWSSSYRSDRLMSFR PIKMDAQEHKISLFEGANFK GNTIEIQGDDAPSLWVYGFS DRVGSVKVSSGTWVGYQYPG YRGYQYLLEPGDFRHWNEWG AFQPQMQSLRRLRDKQWHL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human CRYBB1 (NP_001878.1). |
Additional Info
| Post Translational Modifications | Specific cleavages in the N-terminal arm occur during lens maturation and give rise to truncated forms, leading to impaired oligomerization and protein insolubilization. |
| Function | Crystallins are the dominant structural components of the vertebrate eye lens. |
| Protein Name | Beta-Crystallin B1Beta-B1 Crystallin |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Beta-Crystallin B1 antibodyAnti-Beta-B1 Crystallin antibodyAnti-CRYBB1 antibody |
Information sourced from Uniprot.org