| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CRX (100-200) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CRX |
| Gene ID: |
1406 |
| Uniprot ID: |
CRX_HUMAN |
| Immunogen Region: |
100-200 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CRX (NP_000545.1). |
| Immunogen Sequence: |
QQKQQQQPPGGQAKARPAKR KAGTSPRPSTDVCPDPLGIS DSYSPPLPGPSGSPTTAVAT VSIWSPASESPLPEAQRAGL VASGPSLTSAPYAMTYAPAS A |
| Tissue Specificity | Retina. |
| Function | Transcription factor that binds and transactivates the sequence 5'-TAATCCA-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. |
| Protein Name | Cone-Rod Homeobox Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cone-Rod Homeobox Protein antibodyAnti-CRX antibodyAnti-CORD2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
