Anti-CRX antibody (100-200) (STJ28286)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CRX (100-200) antibody for use in WB, IF, ICC and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRX |
| Gene ID | 1406 |
| Uniprot ID | CRX_HUMAN |
| Immunogen Region | 100-200 |
| Immunogen Sequence | QQKQQQQPPGGQAKARPAKR KAGTSPRPSTDVCPDPLGIS DSYSPPLPGPSGSPTTAVAT VSIWSPASESPLPEAQRAGL VASGPSLTSAPYAMTYAPAS A |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CRX (NP_000545.1). |
Additional Info
| Tissue Specificity | Retina. |
| Function | Transcription factor that binds and transactivates the sequence 5'-TAATCCA-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. |
| Protein Name | Cone-Rod Homeobox Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cone-Rod Homeobox Protein antibodyAnti-CRX antibodyAnti-CORD2 antibody |
Information sourced from Uniprot.org