| Short Description : | Mouse monoclonal anti-CRP for use in LF, FIA and IT in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | LF/FIA/IT |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 6402 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Formulation: | 50 mM citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Storage Instruction: | Store at 2–8 °C, and do not freeze. |
| Immunogen: | Not determined |
| Specificity: | Antibody recognizes human C-reactive protein (CRP) , binding is Ca2+ independent. Does not recognize serum amyloid-P complex |
| Tissue Specificity | Found in plasma. |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Protein Name | C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 |
| Database Links | Reactome: R-HSA-173623 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 antibodyAnti-CRP antibodyAnti-PTX1 antibody |
Information sourced from Uniprot.org