| Short Description : | Rabbit polyclonal anti-Rootletin (220-300 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CROCC |
| Gene ID: | 9696 |
| Uniprot ID: | CROCC_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 220-300 |
| Immunogen Region: | 220-300 aa |
| Specificity: | CROCC Polyclonal Antibody detects endogenous levels of protein. |
| Function | Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Furthermore, is required for the correct positioning of the cilium basal body relative to the cell nucleus, to allow for ciliogenesis. Contributes to centrosome cohesion before mitosis. |
| Protein Name | RootletinCiliary Rootlet Coiled-Coil Protein |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleCilium Basal BodyIn Ciliated CellsAssociated With Ciliary RootletsIn Non-Ciliated CellsLocalized BetweenAround And At The Proximal Ends Of The CentriolesDissociates From The Centrioles At The Onset Of Mitosis And Reassociates With Them At Anaphase |
| Alternative Antibody Names | Anti-Rootletin antibodyAnti-Ciliary Rootlet Coiled-Coil Protein antibodyAnti-CROCC antibodyAnti-KIAA0445 antibody |
Information sourced from Uniprot.org
