Anti-CRH antibody (25-194) (STJ23221)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CRH (25-194) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRH |
| Gene ID | 1392 |
| Uniprot ID | CRF_HUMAN |
| Immunogen Region | 25-194 |
| Immunogen Sequence | LLSRGPVPGARQAPQHPQPL DFFQPPPQSEQPQQPQARPV LLRMGEEYFLRLGNLNKSPA APLSPASSLLAGGSGSRPSP EQATANFFRVLLQQLLLPRR SLDSPAALAERGARNALGGH QEAPERERRSEEPPISLDLT FHLLREVLEMARAEQLAQQA HSNRKLMEII |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 25-194 of human CRH (NP_000747.1). |
Additional Info
| Tissue Specificity | Produced by the hypothalamus and placenta. |
| Function | Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile. |
| Protein Name | CorticoliberinCorticotropin-Releasing FactorCrfCorticotropin-Releasing Hormone |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555Reactome: R-HSA-9022702 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Corticoliberin antibodyAnti-Corticotropin-Releasing Factor antibodyAnti-Crf antibodyAnti-Corticotropin-Releasing Hormone antibodyAnti-CRH antibody |
Information sourced from Uniprot.org