Anti-CREBZF antibody (1-354) (STJ26330)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CREBZF (1-354) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CREBZF |
| Gene ID | 58487 |
| Uniprot ID | ZHANG_HUMAN |
| Immunogen Region | 1-354 |
| Immunogen Sequence | MRHSLTKLLAASGSNSPTRS ESPEPAATCSLPSDLTRAAA GEEETAAAGSPGRKQQFGDE GELEAGRGSRGGVAVRAPSP EEMEEEAIASLPGEETEDMD FLSGLELADLLDPRQPDWHL DPGLSSPGPLSSSGGGSDSG GLWRGDDDDEAAAAEMQRFS DLLQRLLNGIGGCSSSSDSG SAEKRRRKSPGGGGGGGSGN DNNQAATKSPRKAAAAAARL NRLKKKEYVMGLESRVRGL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-354 of human CREBZF (NP_001034707.1). |
Additional Info
| Tissue Specificity | In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lung. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver. |
| Function | Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells. |
| Protein Name | Creb/Atf Bzip Transcription FactorHost Cell Factor-Binding Transcription Factor ZhangfeiHcf-Binding Transcription Factor Zhangfei |
| Database Links | |
| Cellular Localisation | NucleusColocalizes In Promyelocytic Leukemia Protein Nuclear Bodies (Pml-Nb) With Creb3 And Hcfc1 |
| Alternative Antibody Names | Anti-Creb/Atf Bzip Transcription Factor antibodyAnti-Host Cell Factor-Binding Transcription Factor Zhangfei antibodyAnti-Hcf-Binding Transcription Factor Zhangfei antibodyAnti-CREBZF antibodyAnti-ZF antibody |
Information sourced from Uniprot.org