• Anti-CRASH antibody [7B6] (STJ16101068)
  • Anti-CRASH antibody [7B6] (STJ16101068)

Anti-CRASH antibody [7B6] (STJ16101068)

SKU:
STJ16101068

£264.50 - £1,251.50
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Host: Mouse
Applications: ELISA/WB/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CRASH is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: 7B6
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: ELISA (solid phase: 0, 1-100 µg/ml; tracer: 0, 001-100 µg/ml for 30 min at RT). Immunoblotting (1-2 µg/ml). Immunohistology (formalin-fixed: 1-2 µg/ml for 30 min at RT; staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citra
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Gene Symbol: ASRGL1
Gene ID: 80150
Uniprot ID: ASGL1_HUMAN
Immunogen: A BALB/c mouse was immunized with CRASH recombinant protein and synthetic peptide. Fusion partner: SP2/0.
Tissue Specificity Expressed in brain, kidney, testis and tissues of the gastrointestinal tract. Present in sperm (at protein level). Over-expressed in uterine, mammary, prostatic and ovarian carcinoma.
Post Translational Modifications Cleaved into an alpha and beta chain by autocatalysis.this activates the enzyme. The N-terminal residue of the beta subunit is responsible for the nucleophile hydrolase activity.
Function Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine.
Protein Name Isoaspartyl Peptidase/L-Asparaginase
Asparaginase-Like Protein 1
Beta-Aspartyl-Peptidase
Isoaspartyl Dipeptidase
L-Asparagine Amidohydrolase Cleaved Into - Isoaspartyl Peptidase/L-Asparaginase Alpha Chain - Isoaspartyl Peptidase/L-Asparaginase Beta Chain
Database Links Reactome: R-HSA-8964208
Cellular Localisation Cytoplasm
Midpiece Of Sperm Tail
Alternative Antibody Names Anti-Isoaspartyl Peptidase/L-Asparaginase antibody
Anti-Asparaginase-Like Protein 1 antibody
Anti-Beta-Aspartyl-Peptidase antibody
Anti-Isoaspartyl Dipeptidase antibody
Anti-L-Asparagine Amidohydrolase Cleaved Into - Isoaspartyl Peptidase/L-Asparaginase Alpha Chain - Isoaspartyl Peptidase/L-Asparaginase Beta Chain antibody
Anti-ASRGL1 antibody
Anti-ALP antibody
Anti-CRASH antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance