Anti-CRALBP antibody [R05-6O4] (STJA0036710)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human CRALBP
General Information
| Short Description | Rabbit monoclonal anti-CRALBP for use in WB and IP in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R05-6O4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IP 1:50 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | RLBP1 |
| Gene ID | 6017 |
| Uniprot ID | RLBP1_HUMAN |
| Immunogen | A synthesized peptide derived from human CRALBP |
Additional Info
| Tissue Specificity | Retina and pineal gland. Not present in photoreceptor cells but is expressed abundantly in the adjacent retinal pigment epithelium (RPE) and in the Mueller glial cells of the retina. |
| Function | Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. |
| Protein Name | Retinaldehyde-Binding Protein 1Cellular Retinaldehyde-Binding Protein |
| Database Links | Reactome: R-HSA-2187335Reactome: R-HSA-2453902Reactome: R-HSA-9918438 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Retinaldehyde-Binding Protein 1 antibodyAnti-Cellular Retinaldehyde-Binding Protein antibodyAnti-RLBP1 antibodyAnti-CRALBP antibody |
Information sourced from Uniprot.org