Anti-CRABP2 antibody [ZN176] (STJA0033347)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenFull length human recombinant protein of human CRABP2 (NP_001869) produced in E.coli.
General Information
| Short Description | Mouse monoclonal anti-CRABP2 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZN176 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 0.5-1.0 mg/mL |
| Purification | Affinity Chromatography |
| Dilution Range | IHC 1:50-1:100 |
| Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CRABP2 |
| Gene ID | 1382 |
| Uniprot ID | RABP2_HUMAN |
| Immunogen | Full length human recombinant protein of human CRABP2 (NP_001869) produced in E.coli. |
Additional Info
| Post Translational Modifications | Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation. |
| Function | Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. |
| Protein Name | Cellular Retinoic Acid-Binding Protein 2Cellular Retinoic Acid-Binding Protein IiCrabp-Ii |
| Database Links | Reactome: R-HSA-5362517 |
| Cellular Localisation | CytoplasmEndoplasmic ReticulumNucleusUpon Ligand BindingA Conformation Change Exposes A Nuclear Localization Motif And The Protein Is Transported Into The Nucleus |
| Alternative Antibody Names | Anti-Cellular Retinoic Acid-Binding Protein 2 antibodyAnti-Cellular Retinoic Acid-Binding Protein Ii antibodyAnti-Crabp-Ii antibodyAnti-CRABP2 antibody |
Information sourced from Uniprot.org