Anti-CPT1B antibody (313-500 aa) [SRM5266] (STJ11107168)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal CPT1B (313-500 aa) antibody for use in WB, IF, ICC and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5266 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CPT1B |
| Gene ID | 1375 |
| Uniprot ID | CPT1B_HUMAN |
| Immunogen Region | 313-500 aa |
| Immunogen Sequence | FNTTRIPGKDTDVLQHLSDS RHVAVYHKGRFFKLWLYEGA RLLKPQDLEMQFQRILDDPS PPQPGEEKLAALTAGGRVEW AQARQAFFSSGKNKAALEAI ERAAFFVALDEESYSYDPED EASLSLYGKALLHGNCYNRW FDKSFTLISFKNGQLGLNAE HAWADAPIIGHLWEFVLGTD SFHLGYTE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 313-500 of human CPT1B (NP_004368.1). |
Additional Info
| Tissue Specificity | Strong expression in heart and skeletal muscle. No expression in liver and kidney. |
| Function | Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. |
| Protein Name | Carnitine O-Palmitoyltransferase 1 - Muscle IsoformCpt1-MCarnitine O-Palmitoyltransferase I - Muscle IsoformCpt ICpti-MCarnitine Palmitoyltransferase 1bCarnitine Palmitoyltransferase I-Like Protein |
| Database Links | Reactome: R-HSA-200425 |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Carnitine O-Palmitoyltransferase 1 - Muscle Isoform antibodyAnti-Cpt1-M antibodyAnti-Carnitine O-Palmitoyltransferase I - Muscle Isoform antibodyAnti-Cpt I antibodyAnti-Cpti-M antibodyAnti-Carnitine Palmitoyltransferase 1b antibodyAnti-Carnitine Palmitoyltransferase I-Like Protein antibodyAnti-CPT1B antibodyAnti-KIAA1670 antibody |
Information sourced from Uniprot.org