Anti-CPSF2 antibody (450-700) (STJ111646)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CPSF2 (450-700) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CPSF2 |
| Gene ID | 53981 |
| Uniprot ID | CPSF2_HUMAN |
| Immunogen Region | 450-700 |
| Immunogen Sequence | KGSFFKQAKKSYPMFPAPEE RIKWDEYGEIIKPEDFLVPE LQATEEEKSKLESGLTNGDE PMDQDLSDVPTKCISTTESI EIKARVTYIDYEGRSDGDSI KKIINQMKPRQLIIVHGPPE ASQDLAECCRAFGGKDIKVY MPKLHETVDATSETHIYQVR LKDSLVSSLQFCKAKDAELA WIDGVLDMRVSKVDTGVILE EGELKDDGEDSEMQVEAPSD SSVIAQQKAMKSLFGDDEK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 450-700 of human CPSF2 (NP_059133.1). |
Additional Info
| Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing. |
| Protein Name | Cleavage And Polyadenylation Specificity Factor Subunit 2Cleavage And Polyadenylation Specificity Factor 100 Kda SubunitCpsf 100 Kda Subunit |
| Database Links | Reactome: R-HSA-159231Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856Reactome: R-HSA-77595 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cleavage And Polyadenylation Specificity Factor Subunit 2 antibodyAnti-Cleavage And Polyadenylation Specificity Factor 100 Kda Subunit antibodyAnti-Cpsf 100 Kda Subunit antibodyAnti-CPSF2 antibodyAnti-CPSF100 antibodyAnti-KIAA1367 antibody |
Information sourced from Uniprot.org