| Short Description : | Rabbit polyclonal anti-Complexin-4 (47-97 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPLX4 |
| Gene ID: | 339302 |
| Uniprot ID: | CPLX4_HUMAN |
| Immunogen: | Synthesized peptide derived from the human CPLX4 at the amino acid range 47-97 |
| Immunogen Region: | 47-97 aa |
| Specificity: | This antibody detects endogenous levels of CPLX4 at Human/Mouse |
| Function | Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina. Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release. |
| Protein Name | Complexin-4Complexin IvCpx Iv |
| Database Links | |
| Cellular Localisation | SynapseCell MembraneLipid-AnchorEnriched At The Synaptic Terminal |
| Alternative Antibody Names | Anti-Complexin-4 antibodyAnti-Complexin Iv antibodyAnti-Cpx Iv antibodyAnti-CPLX4 antibody |
Information sourced from Uniprot.org
