Anti-CPB2 antibody (321-370 aa) (STJ95898)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CPB2 at the amino acid range 321-370
General Information
| Short Description | Rabbit polyclonal anti-Carboxypeptidase B2 (321-370 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CPB2 |
| Gene ID | 1361 |
| Uniprot ID | CBPB2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CPB2 at the amino acid range 321-370 |
| Immunogen Region | 321-370 aa |
| Specificity | TAFI Polyclonal Antibody detects endogenous levels of TAFI protein. |
Additional Info
| Post Translational Modifications | N-glycosylated. N-glycan at Asn-108: Hex5HexNAc4. |
| Function | Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. |
| Protein Name | Carboxypeptidase B2Carboxypeptidase UCpuPlasma Carboxypeptidase BPcpbThrombin-Activable Fibrinolysis InhibitorTafi |
| Database Links | Reactome: R-HSA-2022377Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Carboxypeptidase B2 antibodyAnti-Carboxypeptidase U antibodyAnti-Cpu antibodyAnti-Plasma Carboxypeptidase B antibodyAnti-Pcpb antibodyAnti-Thrombin-Activable Fibrinolysis Inhibitor antibodyAnti-Tafi antibodyAnti-CPB2 antibody |
Information sourced from Uniprot.org