| Host: |
Rabbit |
| Applications: |
IHC/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Cytochrome c oxidase subunit 6B2 (40-120 aa) is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC-P 1:50-200ELISA-Pep 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
COX6B2 |
| Gene ID: |
125965 |
| Uniprot ID: |
CX6B2_HUMAN |
| Immunogen Region: |
40-120 aa |
| Specificity: |
This antibody detects endogenous levels of human COX6B2 |
| Immunogen: |
Synthesized peptide derived from the human COX6B2 at the amino acid range 40-120 |
| Function | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix. |
| Protein Name | Cytochrome C Oxidase Subunit 6b2Cancer/Testis Antigen 59Ct59Cytochrome C Oxidase Subunit Vib Isoform 2Cox Vib-2Cytochrome C Oxidase Subunit Vib - Testis-Specific Isoform |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinIntermembrane Side |
| Alternative Antibody Names | Anti-Cytochrome C Oxidase Subunit 6b2 antibodyAnti-Cancer/Testis Antigen 59 antibodyAnti-Ct59 antibodyAnti-Cytochrome C Oxidase Subunit Vib Isoform 2 antibodyAnti-Cox Vib-2 antibodyAnti-Cytochrome C Oxidase Subunit Vib - Testis-Specific Isoform antibodyAnti-COX6B2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
