Anti-COX16 antibody (9-59 aa) (STJ196185)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human COX16 at the amino acid range 9-59
General Information
| Short Description | Rabbit polyclonal anti-Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (9-59 aa) for use in IHC and IF in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-200IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | COX16 |
| Gene ID | 51241 |
| Uniprot ID | COX16_HUMAN |
| Immunogen | Synthesized peptide derived from the human COX16 at the amino acid range 9-59 |
| Immunogen Region | 9-59 aa |
| Specificity | This antibody detects endogenous levels of COX16 at Human/Mouse |
Additional Info
| Function | Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines. |
| Protein Name | Cytochrome C Oxidase Assembly Protein Cox16 Homolog - MitochondrialHcox16 |
| Database Links | Reactome: R-HSA-9864848 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cytochrome C Oxidase Assembly Protein Cox16 Homolog - Mitochondrial antibodyAnti-Hcox16 antibodyAnti-COX16 antibodyAnti-C14orf112 antibodyAnti-HSPC203 antibodyAnti-PTD019 antibody |
Information sourced from Uniprot.org