| Short Description : | Rabbit polyclonal anti-Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (9-59 aa) for use in IHC and IF in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC-P 1:50-200IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | COX16 |
| Gene ID: | 51241 |
| Uniprot ID: | COX16_HUMAN |
| Immunogen: | Synthesized peptide derived from the human COX16 at the amino acid range 9-59 |
| Immunogen Region: | 9-59 aa |
| Specificity: | This antibody detects endogenous levels of COX16 at Human/Mouse |
| Function | Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines. |
| Protein Name | Cytochrome C Oxidase Assembly Protein Cox16 Homolog - MitochondrialHcox16 |
| Database Links | Reactome: R-HSA-9864848 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cytochrome C Oxidase Assembly Protein Cox16 Homolog - Mitochondrial antibodyAnti-Hcox16 antibodyAnti-COX16 antibodyAnti-C14orf112 antibodyAnti-HSPC203 antibodyAnti-PTD019 antibody |
Information sourced from Uniprot.org
