| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CORO1B (380-489) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CORO1B |
| Gene ID: |
57175 |
| Uniprot ID: |
COR1B_HUMAN |
| Immunogen Region: |
380-489 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 380-489 of human CORO1B (NP_065174.1). |
| Immunogen Sequence: |
VSGRDADPILISLREAYVPS KQRDLKISRRNVLSDSRPAM APGSSHLGAPASTTTAADAT PSGSLARAGEAGKLEEVMQE LRALRALVKEQGDRICRLEE QLGRMENGDA |
| Post Translational Modifications | Phosphorylation by PKC on Ser-2 regulates the interaction with the Arp2/3 complex and cell motility in fibroblasts. Phosphorylation does not seem to affect subcellular location. |
| Function | Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction. |
| Protein Name | Coronin-1bCoronin-2 |
| Cellular Localisation | CytoplasmCytoskeletonStress FiberLocalized To The Leading Edge In FibroblastsAs Well As Weakly Along Actin Stress Fibers |
| Alternative Antibody Names | Anti-Coronin-1b antibodyAnti-Coronin-2 antibodyAnti-CORO1B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
