Host: | Goat |
Applications: | Pep-ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-Contactin 6/NB-3-Mouse (160-172) is suitable for use in ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000. WB: Preliminary experiments gave an approx 200kDa band in Mouse fetal Brain lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literat |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | CNTN6 |
Gene ID: | 27255 |
Uniprot ID: | CNTN6_HUMAN |
Immunogen Region: | 160-172 |
Accession Number: | NP_059079.2 |
Immunogen Sequence: | NDSPLYVQEDKRR |
Function | Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination. |
Protein Name | Contactin-6 Neural Recognition Molecule Nb-3 Hnb-3 |
Database Links | Reactome: R-HSA-447041 |
Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor |
Alternative Antibody Names | Anti-Contactin-6 antibody Anti-Neural Recognition Molecule Nb-3 antibody Anti-Hnb-3 antibody Anti-CNTN6 antibody |
Information sourced from Uniprot.org