Anti-Contactin 4/Big-2-Mouse antibody (160-172) (STJ72892)

SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ72892-100
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General Information

Short DescriptionGoat polyclonal antibody anti-Contactin 4/Big-2-Mouse (160-172) is suitable for use in ELISA and Western Blot research applications.
ApplicationsPep-ELISA/WB
HostGoat
ReactivityHuman/Mouse/Rat/Dog
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:128000.
WB: Approx 150kDa band observed in Mouse Brain lysates and not in the same lysates from the KO mice (calculated MW of 113kDa according to NP_001103219.1). Recommended concentration: 0.5-1
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20°C on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolCNTN4
Gene ID152330
Uniprot IDCNTN4_HUMAN
Accession NumberNP_001103219.1; NP_766592.2
Immunogen Region160-172
Immunogen SequenceRRADGKPIARK
SpecificityThis antibody is expected to recognize both reported isoforms (NP_001103219.1; NP_766592.2). Reported variants represent identical protein: NP_766592.2, NP_001103221.1

Additional Info

Function Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis.
Protein Name Contactin-4
Brain-Derived Immunoglobulin Superfamily Protein 2
Big-2
Database Links Reactome: R-HSA-163125
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Alternative Antibody Names Anti-Contactin-4 antibody
Anti-Brain-Derived Immunoglobulin Superfamily Protein 2 antibody
Anti-Big-2 antibody
Anti-CNTN4 antibody

Information sourced from Uniprot.org

Citations

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