| Short Description : | Rabbit polyclonal anti-Conserved dopamine neurotrophic factor for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity-purified |
| Dilution Range: | WB 1:6000-1:10000 |
| Formulation: | Concentrated ammonium sulphate in PBS pH 7.4 containing no preservatives. |
| Storage Instruction: | Store antibody stock solution at +4°C upon receipt. DO NOT FREEZE. This product is an (NH4) 2SO4 precipitate. To use, mix well by pipetting or vortexing gently prior use, then withdraw the desired amount of antibody stock solution and dilute into you |
| Gene Symbol: | CDNF |
| Gene ID: | 441549 |
| Uniprot ID: | CDNF_HUMAN |
| Immunogen: | Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant. |
| Immunogen Sequence: | Human |
| Specificity: | CDNF (conserved dopamine neurotrophic factor). |
| Tissue Specificity | Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. |
| Function | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. |
| Protein Name | Cerebral Dopamine Neurotrophic FactorArmet-Like Protein 1Conserved Dopamine Neurotrophic Factor |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cerebral Dopamine Neurotrophic Factor antibodyAnti-Armet-Like Protein 1 antibodyAnti-Conserved Dopamine Neurotrophic Factor antibodyAnti-CDNF antibodyAnti-ARMETL1 antibody |
Information sourced from Uniprot.org