Anti-Connexin-40 antibody (C-Term) (STJA0041026)
SPECIFICATIONS
ClonalityPolyclonal
HostSheep
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide consisting of amino acids 254 to 270 of the C-terminus of rat Cx40 (Cx40/254) conjugated to diphtheria toxoid has been used as the immunogen.
General Information
| Short Description | Sheep polyclonal anti-Connexin-40 (C-Term) for use in IHC and WB in Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Sheep |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Whole serum |
| Dilution Range | WB 0.73611111111111116IHC 1:100-1:250 |
| Storage Instruction | Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at-20°C for a higher stability, and at 2-8°C with an appropriate antibacterial |
Target Information
| Gene Symbol | Gja5 |
| Gene ID | 50563 |
| Uniprot ID | CXA5_RAT |
| Immunogen | A synthetic peptide consisting of amino acids 254 to 270 of the C-terminus of rat Cx40 (Cx40/254) conjugated to diphtheria toxoid has been used as the immunogen. |
| Immunogen Region | C-Term |
| Immunogen Sequence | Rat |
| Specificity | It is reported that the Cx40/254 antibody did not cross react with rat Cx43 but may with Cx45 in Western blots only (Rummery, NM et al 2002). |
Additional Info
| Tissue Specificity | Highly expressed in lung. |
| Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
| Protein Name | Gap Junction Alpha-5 ProteinConnexin-40Cx40 |
| Database Links | Reactome: R-RNO-190861 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell JunctionGap Junction |
| Alternative Antibody Names | Anti-Gap Junction Alpha-5 Protein antibodyAnti-Connexin-40 antibodyAnti-Cx40 antibodyAnti-Gja5 antibodyAnti-Cxn-40 antibody |
Information sourced from Uniprot.org