Host: |
Goat |
Applications: |
Pep-ELISA/IF/IHC |
Reactivity: |
Human/Mouse/Rat/Dog |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-Connective Tissue Growth Factor (C-Term) is suitable for use in ELISA, Immunofluorescence and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
IF-Strong expression of the protein seen in the cytoplasm of NIH3T3 cells. 5µg/mlELISA-antibody detection limit dilution 1:1000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
CCN2 |
Gene ID: |
1490 |
Uniprot ID: |
CCN2_HUMAN |
Immunogen Region: |
C-Term |
Accession Number: |
NP_001892 |
Immunogen Sequence: |
SLYYRKMYGDMA |
Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
Protein Name | Ccn Family Member 2Cellular Communication Network Factor 2Connective Tissue Growth FactorHypertrophic Chondrocyte-Specific Protein 24Insulin-Like Growth Factor-Binding Protein 8Ibp-8Igf-Binding Protein 8Igfbp-8 |
Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-8951671 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Antibody Names | Anti-Ccn Family Member 2 antibodyAnti-Cellular Communication Network Factor 2 antibodyAnti-Connective Tissue Growth Factor antibodyAnti-Hypertrophic Chondrocyte-Specific Protein 24 antibodyAnti-Insulin-Like Growth Factor-Binding Protein 8 antibodyAnti-Ibp-8 antibodyAnti-Igf-Binding Protein 8 antibodyAnti-Igfbp-8 antibodyAnti-CCN2 antibodyAnti-CTGF antibodyAnti-HCS24 antibodyAnti-IGFBP8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance