Anti-Complexin-2 antibody (40-80 aa) (STJ13100095)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 40-80 of human Complexin-2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
General Information
| Short Description | Rabbit polyclonal anti-Complexin-2 (40-80 aa) for use in IHC and WB in Mouse, Rat and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:3000 to 1:4000 is recommended for WB and 1:1000 to 1:2000 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | CPLX2 |
| Gene ID | 10814 |
| Uniprot ID | CPLX2_HUMAN |
| Immunogen | A synthetic peptide from aa region 40-80 of human Complexin-2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
| Immunogen Region | 40-80 aa |
| Specificity | Specific for Complexin-2. |
Additional Info
| Function | Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis. |
| Protein Name | Complexin-2Complexin IiCpx IiSynaphin-1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolPresynapseNucleusPerikaryonTranslocated From The Perikaryon To The Presynaptic Terminals During Maturation Of Neuronal CellsIn Mast CellsCytosol And NucleusBecomes Enriched Near Plasma Membrane Following Stimulation |
| Alternative Antibody Names | Anti-Complexin-2 antibodyAnti-Complexin Ii antibodyAnti-Cpx Ii antibodyAnti-Synaphin-1 antibodyAnti-CPLX2 antibody |
Information sourced from Uniprot.org