Anti-Colon carcinoma laminin binding protein antibody (90-130 aa) (STJ13100274)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 90-130 of human RSSA conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
General Information
| Short Description | Rabbit polyclonal anti-Colon carcinoma laminin binding protein (90-130 aa) for use in IHC and WB in Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:1000 is recommended. The optimal dilution should be determined by the end user. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | RPSA |
| Gene ID | 3921 |
| Uniprot ID | RSSA_HUMAN |
| Immunogen | A synthetic peptide from aa region 90-130 of human RSSA conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
| Immunogen Region | 90-130 aa |
| Specificity | Specific for Colon carcinoma laminin binding protein. |
Additional Info
| Function | Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. (Microbial infection) Acts as a receptor for the Adeno-associated viruses 2,3,8 and 9. (Microbial infection) Acts as a receptor for the Dengue virus. (Microbial infection) Acts as a receptor for the Sindbis virus. (Microbial infection) Acts as a receptor for the Venezuelan equine encephalitis virus. (Microbial infection) Acts as a receptor for the pathogenic prion protein. (Microbial infection) Acts as a receptor for bacteria. |
| Protein Name | Small Ribosomal Subunit Protein Us237 Kda Laminin Receptor Precursor37lrp37/67 Kda Laminin ReceptorLrp/Lr40s Ribosomal Protein Sa67 Kda Laminin Receptor67lrColon Carcinoma Laminin-Binding ProteinLaminin Receptor 1LamrLaminin-Binding Protein Precursor P40Lbp/P40Multidrug Resistance-Associated Protein Mgr1-AgNem/1chd4 |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6791226Reactome: R-HSA-72649Reactome: R-HSA-72689Reactome: R-HSA-72695Reactome: R-HSA-72702Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-9735869Reactome: R-HSA-9754678Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | Cell MembraneCytoplasmNucleus67lr Is Found At The Surface Of The Plasma MembraneWith Its C-Terminal Laminin-Binding Domain Accessible To Extracellular Ligands37lrp Is Found At The Cell SurfaceIn The Cytoplasm And In The NucleusColocalizes With Ppp1r16b In The Cell Membrane |
| Alternative Antibody Names | Anti-Small Ribosomal Subunit Protein Us2 antibodyAnti-37 Kda Laminin Receptor Precursor antibodyAnti-37lrp antibodyAnti-37/67 Kda Laminin Receptor antibodyAnti-Lrp/Lr antibodyAnti-40s Ribosomal Protein Sa antibodyAnti-67 Kda Laminin Receptor antibodyAnti-67lr antibodyAnti-Colon Carcinoma Laminin-Binding Protein antibodyAnti-Laminin Receptor 1 antibodyAnti-Lamr antibodyAnti-Laminin-Binding Protein Precursor P40 antibodyAnti-Lbp/P40 antibodyAnti-Multidrug Resistance-Associated Protein Mgr1-Ag antibodyAnti-Nem/1chd4 antibodyAnti-RPSA antibodyAnti-LAMBR antibodyAnti-LAMR1 antibody |
Information sourced from Uniprot.org