Anti-Collagen VII antibody (750-800 aa) (STJ13100109)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 750-800 of rat collagen Vii conjugated to blue carrier protein was used as the antigen. The peptide is homologous with mouse sequence.
General Information
| Short Description | Rabbit polyclonal anti-Collagen VII (750-800 aa) for use in IHC and WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 100 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Col7a1 |
| Gene ID | 12836 |
| Uniprot ID | CO7A1_MOUSE |
| Immunogen | A synthetic peptide from aa region 750-800 of rat collagen Vii conjugated to blue carrier protein was used as the antigen. The peptide is homologous with mouse sequence. |
| Immunogen Region | 750-800 aa |
| Specificity | Specific for Collagen alpha-1 (VII) chain. |
Additional Info
| Function | Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. |
| Protein Name | Collagen Alpha-1(Vii ChainLong-Chain CollagenLc Collagen |
| Database Links | Reactome: R-MMU-1442490Reactome: -MMU-1474244Reactome: -MMU-1650814Reactome: -MMU-204005Reactome: -MMU-216083Reactome: -MMU-2214320Reactome: -MMU-5694530Reactome: -MMU-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement Membrane |
| Alternative Antibody Names | Anti-Collagen Alpha-1(Vii Chain antibodyAnti-Long-Chain Collagen antibodyAnti-Lc Collagen antibodyAnti-Col7a1 antibody |
Information sourced from Uniprot.org