| Host: |
Mouse |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Collagen IV is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
ZM177 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2a/Kappa |
| Formulation: |
Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: |
Affinity purified |
| Dilution Range: |
1:100-200 |
| Storage Instruction: |
Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: |
COL6A5 |
| Gene ID: |
256076 |
| Uniprot ID: |
CO6A5_HUMAN |
| Specificity: |
Positive control: Skin |
| Immunogen: |
Purified human Collagen IV protein |
| Tissue Specificity | Expressed in skin, followed by lung, small intestine, colon and testis. In skin, it is expressed in the epidermis with strongest staining in suprabasal viable layers. In ATOD patients, it is absent in the most differentiated upper spinous and granular layers (at protein level). |
| Post Translational Modifications | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. |
| Function | Collagen VI acts as a cell-binding protein. |
| Protein Name | Collagen Alpha-5(Vi ChainCollagen Alpha-1(Xxix ChainVon Willebrand Factor A Domain-Containing Protein 4 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1650814Reactome: R-HSA-186797Reactome: R-HSA-2022090Reactome: R-HSA-216083Reactome: R-HSA-3000178Reactome: R-HSA-419037Reactome: R-HSA-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixDeposed In The Extracellular Matrix Of Skeletal Muscle |
| Alternative Antibody Names | Anti-Collagen Alpha-5(Vi Chain antibodyAnti-Collagen Alpha-1(Xxix Chain antibodyAnti-Von Willebrand Factor A Domain-Containing Protein 4 antibodyAnti-COL6A5 antibodyAnti-COL29A1 antibodyAnti-VWA4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
