Anti-Collagen I alpha 2 antibody [R06-8D8] (STJA0035790)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Collagen I
General Information
| Short Description | Rabbit monoclonal anti-Collagen I alpha 2 for use in WB and IHC-P in Human and Cow samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-8D8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | COL1A2 |
| Gene ID | 1278 |
| Uniprot ID | CO1A2_HUMAN |
| Immunogen | A synthesized peptide derived from human Collagen I |
Additional Info
| Tissue Specificity | Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite. |
| Post Translational Modifications | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. |
| Function | Type I collagen is a member of group I collagen (fibrillar forming collagen). |
| Protein Name | Collagen Alpha-2(I ChainAlpha-2 Type I Collagen |
| Database Links | Reactome: R-HSA-114604Reactome: R-HSA-1442490Reactome: R-HSA-1474244Reactome: R-HSA-1650814Reactome: R-HSA-198933Reactome: R-HSA-2022090Reactome: R-HSA-202733Reactome: R-HSA-216083Reactome: R-HSA-2173796Reactome: R-HSA-2214320Reactome: R-HSA-2243919Reactome: R-HSA-3000170Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-3000480Reactome: R-HSA-430116Reactome: R-HSA-6785807Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-8874081Reactome: R-HSA-8948216Reactome: R-HSA-9845619Reactome: R-HSA-9845620Reactome: R-HSA-9845621Reactome: R-HSA-9845622Reactome: R-HSA-9846298 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Collagen Alpha-2(I Chain antibodyAnti-Alpha-2 Type I Collagen antibodyAnti-COL1A2 antibody |
Information sourced from Uniprot.org