Anti-COLEC12 antibody (STJ192053)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Collectin-12 for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | COLEC12 |
| Gene ID | 81035 |
| Uniprot ID | COL12_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | COL12 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Also binds to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid-beta in Alzheimer disease. |
| Protein Name | Collectin-12Collectin Placenta Protein 1Cl-P1Hcl-P1Nurse Cell Scavenger Receptor 2Scavenger Receptor Class A Member 4Scavenger Receptor With C-Type Lectin |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-3000480 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane ProteinForms Clusters On The Cell Surface |
| Alternative Antibody Names | Anti-Collectin-12 antibodyAnti-Collectin Placenta Protein 1 antibodyAnti-Cl-P1 antibodyAnti-Hcl-P1 antibodyAnti-Nurse Cell Scavenger Receptor 2 antibodyAnti-Scavenger Receptor Class A Member 4 antibodyAnti-Scavenger Receptor With C-Type Lectin antibodyAnti-COLEC12 antibodyAnti-CLP1 antibodyAnti-NSR2 antibodyAnti-SCARA4 antibodyAnti-SRCL antibody |
Information sourced from Uniprot.org