| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Collectin-12 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
COLEC12 |
| Gene ID: |
81035 |
| Uniprot ID: |
COL12_HUMAN |
| Specificity: |
COL12 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Function | Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid-beta in Alzheimer disease. |
| Protein Name | Collectin-12Collectin Placenta Protein 1Cl-P1Hcl-P1Nurse Cell Scavenger Receptor 2Scavenger Receptor Class A Member 4Scavenger Receptor With C-Type Lectin |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-3000480 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane ProteinForms Clusters On The Cell Surface |
| Alternative Antibody Names | Anti-Collectin-12 antibodyAnti-Collectin Placenta Protein 1 antibodyAnti-Cl-P1 antibodyAnti-Hcl-P1 antibodyAnti-Nurse Cell Scavenger Receptor 2 antibodyAnti-Scavenger Receptor Class A Member 4 antibodyAnti-Scavenger Receptor With C-Type Lectin antibodyAnti-COLEC12 antibodyAnti-CLP1 antibodyAnti-NSR2 antibodyAnti-SCARA4 antibodyAnti-SRCL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
