| Short Description : | Rabbit polyclonal anti-Coilin for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | COIL |
| Gene ID: | 8161 |
| Uniprot ID: | COIL_HUMAN |
| Immunogen: | Synthesized peptide derived from human Coilin |
| Specificity: | This antibody detects endogenous levels of Coilin at Human |
| Post Translational Modifications | Symmetrical dimethylation of arginine residues within the RG repeat region enhances affinity for SMN, and thus localization of SMN complexes to CBs. Phosphorylated by VRK1. Phosphorylation during mitosis is associated with disassembly of CBs. |
| Function | Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs. |
| Protein Name | CoilinP80-Coilin |
| Database Links | |
| Cellular Localisation | NucleusCajal Body |
| Alternative Antibody Names | Anti-Coilin antibodyAnti-P80-Coilin antibodyAnti-COIL antibodyAnti-CLN80 antibody |
Information sourced from Uniprot.org
