Anti-COASY antibody [R38-9L-7] (STJA0035534)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human COASY
General Information
| Short Description | Rabbit monoclonal anti-COASY for use in WB and FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R38-9L-7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000FC 1:50 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | COASY |
| Gene ID | 80347 |
| Uniprot ID | COASY_HUMAN |
| Immunogen | A synthesized peptide derived from human COASY |
Additional Info
| Tissue Specificity | Expressed in all tissues examined including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocyte. Lowest expression in peripheral blood leukocytes and highest in kidney and liver. Isoform 2 is expressed mainly in the brain. |
| Function | Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain.the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation. |
| Protein Name | Bifunctional Coenzyme A SynthaseCoa SynthaseNbpPov-2 Includes - Phosphopantetheine AdenylyltransferaseDephospho-Coa PyrophosphorylasePantetheine-Phosphate AdenylyltransferasePpat - Dephospho-Coa KinaseDpckDephosphocoenzyme A KinaseDpcoak |
| Database Links | Reactome: R-HSA-196783 |
| Cellular Localisation | CytoplasmMitochondrion MatrixThe Protein Is Mainly Present In The Mitochondrial MatrixProbably Anchored To The Inner Mitochondrial MembraneBut Is Also Present In Cell Lysate |
| Alternative Antibody Names | Anti-Bifunctional Coenzyme A Synthase antibodyAnti-Coa Synthase antibodyAnti-Nbp antibodyAnti-Pov-2 Includes - Phosphopantetheine Adenylyltransferase antibodyAnti-Dephospho-Coa Pyrophosphorylase antibodyAnti-Pantetheine-Phosphate Adenylyltransferase antibodyAnti-Ppat - Dephospho-Coa Kinase antibodyAnti-Dpck antibodyAnti-Dephosphocoenzyme A Kinase antibodyAnti-Dpcoak antibodyAnti-COASY antibodyAnti-PSEC0106 antibody |
Information sourced from Uniprot.org