Anti-CNTNAP2 antibody (ECD) (STJ13100907)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from extracellular domain of mouse Contactin associated protein like 2 (CNTNAP2) conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-CNTNAP2 (ECD) for use in IHC and WB in Mouse, Rat and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Cntnap2 |
| Gene ID | 66797 |
| Uniprot ID | CNTP2_MOUSE |
| Immunogen | A synthetic peptide from extracellular domain of mouse Contactin associated protein like 2 (CNTNAP2) conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | ECD |
| Specificity | Specific for CNTNAP2. |
Additional Info
| Function | Required for gap junction formation. Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction (Probable). |
| Protein Name | Contactin-Associated Protein-Like 2Cell Recognition Molecule Caspr2 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionAxonCell JunctionParanodal Septate JunctionExpressed In The Juxtaparadonal Region |
| Alternative Antibody Names | Anti-Contactin-Associated Protein-Like 2 antibodyAnti-Cell Recognition Molecule Caspr2 antibodyAnti-Cntnap2 antibodyAnti-Kiaa0868 antibody |
Information sourced from Uniprot.org