Anti-CNTFR antibody (90-342) (STJ23187)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CNTFR (90-342) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:400-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CNTFR |
| Gene ID | 1271 |
| Uniprot ID | CNTFR_HUMAN |
| Immunogen Region | 90-342 |
| Immunogen Sequence | FHRDSWHLRHQVLLHVGLPP REPVLSCRSNTYPKGFYCSW HLPTPTYIPNTFNVTVLHGS KIMVCEKDPALKNRCHIRYM HLFSTIKYKVSISVSNALGH NATAITFDEFTIVKPDPPEN VVARPVPSNPRRLEVTWQTP STWPDPESFPLKFFLRYRPL ILDQWQHVELSDGTAHTITD AYAGKEYIIQVAAKDNEIGT WSDWSVAAHATPWTEEPRHL TTEAQAAETTTSTTSSLAP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 90-342 of human CNTFR (NP_671693.1). |
Additional Info
| Tissue Specificity | Nervous system and skeletal muscle. |
| Function | Binds to CNTF. The alpha subunit provides the receptor specificity. Receptor for heterodimeric neurotropic cytokine composed of CLCF1/CLC and CRLF1/CLF-1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and IL27RA/WSX1. |
| Protein Name | Ciliary Neurotrophic Factor Receptor Subunit AlphaCntf Receptor Subunit AlphaCntfr-Alpha |
| Database Links | Reactome: R-HSA-6788467 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Ciliary Neurotrophic Factor Receptor Subunit Alpha antibodyAnti-Cntf Receptor Subunit Alpha antibodyAnti-Cntfr-Alpha antibodyAnti-CNTFR antibody |
Information sourced from Uniprot.org