Anti-CNTD1 antibody (1-120) (STJ119844)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CNTD1 (1-120) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CNTD1 |
| Gene ID | 124817 |
| Uniprot ID | CNTD1_HUMAN |
| Immunogen Region | 1-120 |
| Immunogen Sequence | MVKQAENICRQATIQPRDNK RESQNWRALKQQLVNKFTLR LVSCVQLASKLSFRNKIISN ITVLNFLQALGYLHTKEELL ESELDVLKSLNFRINLPTPL AYVETLLEVLGYNGCLVPAM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human CNTD1 (NP_001317151.1). |
Additional Info
| Function | Plays a role in the different steps of crossover formation during meiotic recombination. Participates in the crossover differentiation step of crossover-specific recombination intermediates through its interaction with PRR19. In addition, stimulates crossover formation through the interactions with RFC3 and RFC4 and simultaneously regulates cell-cycle progression through interactions with CDC34 and subsequent ubiquitination of WEE1. May also participates in an active deselection process that destabilizes or removes excess pre-CO intermediates. |
| Protein Name | Cyclin N-Terminal Domain-Containing Protein 1 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmChromosomeShuttles Between The Nucleus And Cytoplasm In A Stage-Specific Manner Of Prophase I CellsCo-Localized At Crossover Sites With Prr19 |
| Alternative Antibody Names | Anti-Cyclin N-Terminal Domain-Containing Protein 1 antibodyAnti-CNTD1 antibodyAnti-CNTD antibody |
Information sourced from Uniprot.org