Anti-CNP antibody (150-421) (STJ28022)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CNP (150-421) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CNP |
| Gene ID | 1267 |
| Uniprot ID | CN37_HUMAN |
| Immunogen Region | 150-421 |
| Immunogen Sequence | PKTAWRLDCAQLKEKNQWQL SADDLKKLKPGLEKDFLPLY FGWFLTKKSSETLRKAGQVF LEELGNHKAFKKELRQFVPG DEPREKMDLVTYFGKRPPGV LHCTTKFCDYGKAPGAEEYA QQDVLKKSYSKAFTLTISAL FVTPKTTGARVELSEQQLQL WPSDVDKLSPTDNLPRGSRA HITLGCAADVEAVQTGLDLL EILRQEKGGSRGEEVGELSR GKLYSLGNGRWMLTLAKNM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 150-421 of human CNPasease (NP_149124.3). |
Additional Info
| Function | Catalyzes the formation of 2'-nucleotide products from 2',3'-cyclic substrates. May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. |
| Protein Name | 2' -3'-Cyclic-Nucleotide 3'-PhosphodiesteraseCnpCnpase |
| Database Links | |
| Cellular Localisation | MembraneLipid-AnchorMelanosomeFirmly Bound To Membrane Structures Of Brain White Matter |
| Alternative Antibody Names | Anti-2' -3'-Cyclic-Nucleotide 3'-Phosphodiesterase antibodyAnti-Cnp antibodyAnti-Cnpase antibodyAnti-CNP antibody |
Information sourced from Uniprot.org