Anti-CNN1 antibody (100-200 aa) [ABT133] (STJ197107)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenSynthesized peptide derived from the human Calponin-1 at the amino acid range 100-200
General Information
| Short Description | Mouse monoclonal anti-Calponin-1 (100-200 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ABT133 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC-P 1:100-500WB 1:200-1000IF 1:100-500 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CNN1 |
| Gene ID | 1264 |
| Uniprot ID | CNN1_HUMAN |
| Immunogen | Synthesized peptide derived from the human Calponin-1 at the amino acid range 100-200 |
| Immunogen Region | 100-200 aa |
| Specificity | The antibody can specifically recognize human and mouse calponin-1 protein. In western blotting of Hela, LnCap and mouse muscle lysates, the antibody can label a 34KDa band corresponding to calponin- |
Additional Info
| Function | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. |
| Protein Name | Calponin-1Basic CalponinCalponin H1 - Smooth Muscle |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Calponin-1 antibodyAnti-Basic Calponin antibodyAnti-Calponin H1 - Smooth Muscle antibodyAnti-CNN1 antibody |
Information sourced from Uniprot.org