Anti-CNGA3 antibody (STJ190727)

SKU:
STJ190727

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cyclic nucleotide-gated cation channel alpha-3 is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CNGA3
Gene ID: 1261
Uniprot ID: CNGA3_HUMAN
Specificity: CNGA3 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3. Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
Protein Name Cyclic Nucleotide-Gated Cation Channel Alpha-3
Cone Photoreceptor Cgmp-Gated Channel Subunit Alpha
Cyclic Nucleotide-Gated Channel Alpha-3
Cng Channel Alpha-3
Cng-3
Cng3
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Cyclic Nucleotide-Gated Cation Channel Alpha-3 antibody
Anti-Cone Photoreceptor Cgmp-Gated Channel Subunit Alpha antibody
Anti-Cyclic Nucleotide-Gated Channel Alpha-3 antibody
Anti-Cng Channel Alpha-3 antibody
Anti-Cng-3 antibody
Anti-Cng3 antibody
Anti-CNGA3 antibody
Anti-CNCG3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance