Anti-CNEP1R1 antibody (25-75 aa) (STJ194528)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human NEPR1 at the amino acid range 25-75
General Information
| Short Description | Rabbit polyclonal anti-Nuclear envelope phosphatase-regulatory subunit 1 (25-75 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CNEP1R1 |
| Gene ID | 255919 |
| Uniprot ID | NEPR1_HUMAN |
| Immunogen | Synthesized peptide derived from the human NEPR1 at the amino acid range 25-75 |
| Immunogen Region | 25-75 aa |
| Specificity | This antibody detects endogenous levels of NEPR1 at Human/Mouse |
Additional Info
| Function | Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. |
| Protein Name | Nuclear Envelope Phosphatase-Regulatory Subunit 1Nep1-R1Transmembrane Protein 188 |
| Database Links | Reactome: R-HSA-4419969 |
| Cellular Localisation | Nucleus MembraneMulti-Pass Membrane ProteinCytoplasmFilamentous Pattern In The Cytoplasm |
| Alternative Antibody Names | Anti-Nuclear Envelope Phosphatase-Regulatory Subunit 1 antibodyAnti-Nep1-R1 antibodyAnti-Transmembrane Protein 188 antibodyAnti-CNEP1R1 antibodyAnti-C16orf69 antibodyAnti-TMEM188 antibody |
Information sourced from Uniprot.org