| Function | Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. |
| Protein Name | Nuclear Envelope Phosphatase-Regulatory Subunit 1Nep1-R1Transmembrane Protein 188 |
| Database Links | Reactome: R-HSA-4419969 |
| Cellular Localisation | Nucleus MembraneMulti-Pass Membrane ProteinCytoplasmFilamentous Pattern In The Cytoplasm |
| Alternative Antibody Names | Anti-Nuclear Envelope Phosphatase-Regulatory Subunit 1 antibodyAnti-Nep1-R1 antibodyAnti-Transmembrane Protein 188 antibodyAnti-CNEP1R1 antibodyAnti-C16orf69 antibodyAnti-TMEM188 antibody |
Information sourced from Uniprot.org