Anti-CNDP2/CPGL antibody (1-475aa) [AT15E5] (STJA0041935)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human CNDP2 (1-475aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-CNDP2/CPGL (1-475aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT15E5 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CNDP2 |
| Gene ID | 55748 |
| Uniprot ID | CNDP2_HUMAN |
| Accession Number | NP_060705 |
| Immunogen | Recombinant human CNDP2 (1-475aa) purified from E. coli |
| Immunogen Region | 1-475aa |
Additional Info
| Tissue Specificity | Isoform 1: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes. Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level). Isoform 2: Broadly expressed in fetal tissues. Expressed in adult liver and placenta. |
| Function | Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. Mediates threonyl dipeptide catabolism in a tissue-specific way. Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism. Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis. Plays a role in the regulation of cell cycle arrest and apoptosis. |
| Protein Name | Cytosolic Non-Specific DipeptidaseCndp Dipeptidase 2Glutamate Carboxypeptidase-Like Protein 1Peptidase AThreonyl Dipeptidase |
| Database Links | Reactome: R-HSA-174403Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cytosolic Non-Specific Dipeptidase antibodyAnti-Cndp Dipeptidase 2 antibodyAnti-Glutamate Carboxypeptidase-Like Protein 1 antibodyAnti-Peptidase A antibodyAnti-Threonyl Dipeptidase antibodyAnti-CNDP2 antibodyAnti-CN2 antibodyAnti-CPGL antibodyAnti-HEL-S-13 antibodyAnti-PEPA antibody |
Information sourced from Uniprot.org