| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CCHC-type zinc finger nucleic acid binding protein (60-140 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CNBP |
| Gene ID: |
7555 |
| Uniprot ID: |
CNBP_HUMAN |
| Immunogen Region: |
60-140 aa |
| Specificity: |
CNBP Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 60-140 |
| Post Translational Modifications | Arginine methylation by PRMT1 in the Arg/Gly-rich region impedes RNA binding. |
| Function | Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression. Has a role as transactivator of the Myc promoter. Binds single-stranded RNA in a sequence-specific manner. Isoform 1: Binds G-rich elements in target mRNA coding sequences. Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs. Isoform 2: Binds to RNA. Isoform 4: Binds to RNA. Isoform 5: Binds to RNA. Isoform 6: Binds to RNA. Isoform 8: Binds to RNA. |
| Protein Name | Cchc-Type Zinc Finger Nucleic Acid Binding ProteinCellular Nucleic Acid-Binding ProteinCnbpZinc Finger Protein 9 |
| Database Links | Reactome: R-HSA-9705671 |
| Cellular Localisation | NucleusCytoplasmEndoplasmic ReticulumIsoform 1: CytoplasmIsoform 2: CytoplasmIsoform 4: CytoplasmIsoform 5: CytoplasmIsoform 6: CytoplasmIsoform 8: Cytoplasm |
| Alternative Antibody Names | Anti-Cchc-Type Zinc Finger Nucleic Acid Binding Protein antibodyAnti-Cellular Nucleic Acid-Binding Protein antibodyAnti-Cnbp antibodyAnti-Zinc Finger Protein 9 antibodyAnti-CNBP antibodyAnti-RNF163 antibodyAnti-ZNF9 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
