| Host: | Goat |
| Applications: | Pep-ELISA/WB-Trf/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CMA1 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: In transfected HEK293 transiently expressing full-length Human CMA1 (myc and DYKDDDDK tagged) , a band of approx. 35kDa was observed. No bands were observed in mock-transfected HEK293 |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CMA1 |
| Gene ID: | 1215 |
| Uniprot ID: | CMA1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001827.1 |
| Immunogen Sequence: | QFRHPKYNTSTLHHD |
| Function | Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. |
| Protein Name | ChymaseAlpha-ChymaseMast Cell Protease I |
| Database Links | Reactome: R-HSA-1433557Reactome: R-HSA-1592389Reactome: R-HSA-2022377 |
| Cellular Localisation | SecretedCytoplasmic GranuleMast Cell Granules |
| Alternative Antibody Names | Anti-Chymase antibodyAnti-Alpha-Chymase antibodyAnti-Mast Cell Protease I antibodyAnti-CMA1 antibodyAnti-CYH antibodyAnti-CYM antibody |
Information sourced from Uniprot.org
