| Post Translational Modifications | Proteolytically cleaved by protease PARL. ATP-dependent protein disaggregase activity is stimulated by PARL-mediated cleavage of the N-terminal autoinhibitory peptide. |
| Function | Functions as a regulatory ATPase and participates in secretion/protein trafficking process. Has ATP-dependent protein disaggregase activity and is required to maintain the solubility of key mitochondrial proteins. Involved in mitochondrial-mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and pro-inflammatory cytokine IL6. Plays a role in granulocyte differentiation. |
| Protein Name | Mitochondrial DisaggregaseSuppressor Of Potassium Transport Defect 3 Cleaved Into - Mitochondrial Disaggregase - Cleaved Form |
| Database Links | |
| Cellular Localisation | Mitochondrion Intermembrane Space |
| Alternative Antibody Names | Anti-Mitochondrial Disaggregase antibodyAnti-Suppressor Of Potassium Transport Defect 3 Cleaved Into - Mitochondrial Disaggregase - Cleaved Form antibodyAnti-CLPB antibodyAnti-SKD3 antibody |
Information sourced from Uniprot.org
