Anti-CLK1 antibody (101-150 aa) (STJ92336)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CLK1 at the amino acid range 101-150
General Information
| Short Description | Rabbit polyclonal anti-Dual specificity protein kinase CLK1 (101-150 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CLK1 |
| Gene ID | 1195 |
| Uniprot ID | CLK1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CLK1 at the amino acid range 101-150 |
| Immunogen Region | 101-150 aa |
| Specificity | CLK1 Polyclonal Antibody detects endogenous levels of CLK1 protein. |
Additional Info
| Post Translational Modifications | Autophosphorylates on all three types of residues. |
| Function | Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. |
| Protein Name | Dual Specificity Protein Kinase Clk1Cdc-Like Kinase 1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dual Specificity Protein Kinase Clk1 antibodyAnti-Cdc-Like Kinase 1 antibodyAnti-CLK1 antibodyAnti-CLK antibody |
Information sourced from Uniprot.org