Anti-CLEC4C antibody (91-140 aa) (STJ98744)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide from the human protein at the amino acid range 91-140
General Information
| Short Description | Rabbit polyclonal anti-C-type lectin domain family 4 member C (91-140 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CLEC4C |
| Gene ID | 170482 |
| Uniprot ID | CLC4C_HUMAN |
| Immunogen | Synthetic peptide from the human protein at the amino acid range 91-140 |
| Immunogen Region | 91-140 aa |
| Specificity | The antibody detects endogenous CD303 |
Additional Info
| Function | Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. |
| Protein Name | C-Type Lectin Domain Family 4 Member CBlood Dendritic Cell Antigen 2Bdca-2C-Type Lectin Superfamily Member 7Dendritic LectinCd Antigen Cd303 |
| Database Links | Reactome: R-HSA-5621480Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 4 Member C antibodyAnti-Blood Dendritic Cell Antigen 2 antibodyAnti-Bdca-2 antibodyAnti-C-Type Lectin Superfamily Member 7 antibodyAnti-Dendritic Lectin antibodyAnti-Cd Antigen Cd303 antibodyAnti-CLEC4C antibodyAnti-BDCA2 antibodyAnti-CLECSF11 antibodyAnti-CLECSF7 antibodyAnti-DLEC antibodyAnti-HECL antibodyAnti-UNQ9361 antibodyAnti-PRO34150 antibody |
Information sourced from Uniprot.org