Anti-Cleaved-MMP8-Leu101 antibody (100-101) (STJA0005895)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MMP8 (Cleaved-Leu101)
General Information
| Short Description | Rabbit polyclonal anti-Cleaved-Neutrophil collagenase-Leu101 (100-101) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-p 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MMP8 |
| Gene ID | 4317 |
| Uniprot ID | MMP8_HUMAN |
| Immunogen | Synthesized peptide derived from human MMP8 (Cleaved-Leu101) |
| Immunogen Region | 100-101 |
| Specificity | This antibody detects endogenous levels of Human, Mouse, Rat MMP8 (Cleaved-Leu101, protein was cleaved amino acid sequence between 100-101 ) |
Additional Info
| Tissue Specificity | Neutrophils. |
| Function | Can degrade fibrillar type I, II, and III collagens. |
| Protein Name | Neutrophil CollagenaseMatrix Metalloproteinase-8Mmp-8Pmnl CollagenasePmnl-Cl |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasmic GranuleSecretedExtracellular SpaceExtracellular MatrixStored In Intracellular Granules |
| Alternative Antibody Names | Anti-Neutrophil Collagenase antibodyAnti-Matrix Metalloproteinase-8 antibodyAnti-Mmp-8 antibodyAnti-Pmnl Collagenase antibodyAnti-Pmnl-Cl antibodyAnti-MMP8 antibodyAnti-CLG1 antibody |
Information sourced from Uniprot.org