Anti-Cleaved-MMP21-Ser145 antibody (144-145) (STJA0005892)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MMP21 (Cleaved-Ser145)
General Information
| Short Description | Rabbit polyclonal anti-Cleaved-Matrix metalloproteinase-21-Ser145 (144-145) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-p 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MMP21 |
| Gene ID | 118856 |
| Uniprot ID | MMP21_HUMAN |
| Immunogen | Synthesized peptide derived from human MMP21 (Cleaved-Ser145) |
| Immunogen Region | 144-145 |
| Specificity | This antibody detects endogenous levels of Human, Mouse MMP21 (Cleaved-Ser145, protein was cleaved amino acid sequence between 144-145 ) |
Additional Info
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway. Cleaves alpha-1-antitrypsin. |
| Protein Name | Matrix Metalloproteinase-21Mmp-21 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-21 antibodyAnti-Mmp-21 antibodyAnti-MMP21 antibody |
Information sourced from Uniprot.org