| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Cleaved-Matrix metalloproteinase-21-Ser145 (144-145) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-p 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MMP21 |
| Gene ID: |
118856 |
| Uniprot ID: |
MMP21_HUMAN |
| Immunogen Region: |
144-145 |
| Specificity: |
This antibody detects endogenous levels of Human, Mouse MMP21 (Cleaved-Ser145, protein was cleaved amino acid sequence between 144-145 ) |
| Immunogen: |
Synthesized peptide derived from human MMP21 (Cleaved-Ser145) |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway. Cleaves alpha-1-antitrypsin. |
| Protein Name | Matrix Metalloproteinase-21Mmp-21 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-21 antibodyAnti-Mmp-21 antibodyAnti-MMP21 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
